Human PDK4 activation kit by CRISPRa

CAT#: GA103463

PDK4 CRISPRa kit - CRISPR gene activation of human pyruvate dehydrogenase kinase 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PDK4
• Locus ID: 5166
• Kit Components:

  GA103463G1, PDK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103463G2, PDK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103463G3, PDK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002612
• Synonyms: FLJ40832
• Summary: 'This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008]'