Human Enkephalin (PENK) activation kit by CRISPRa

CAT#: GA103474

PENK CRISPRa kit - CRISPR gene activation of human proenkephalin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PENK
• Locus ID: 5179
• Kit Components:

  GA103474G1, Enkephalin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103474G2, Enkephalin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103474G3, Enkephalin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135690, NM_006211
• Synonyms: PE; PENK-A
• Summary: 'This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the pentapeptide opioids Met-enkephalin and Leu-enkephalin, which are stored in synaptic vesicles, then released into the synapse where they bind to mu- and delta-opioid receptors to modulate the perception of pain. Other non-opioid cleavage products may function in distinct biological activities. [provided by RefSeq, Jul 2015]'