Human PGM3 activation kit by CRISPRa

CAT#: GA103518

PGM3 CRISPRa kit - CRISPR gene activation of human phosphoglucomutase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PGM3
• Locus ID: 5238
• Kit Components:

  GA103518G1, PGM3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103518G2, PGM3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103518G3, PGM3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199917, NM_001199918, NM_001199919, NM_015599, NM_001367286, NR_159812, NM_001367287
• Synonyms: AGM1; IMD23; PAGM; PGM 3
• Summary: 'This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]'