Human PMM1 activation kit by CRISPRa

CAT#: GA103627

PMM1 CRISPRa kit - CRISPR gene activation of human phosphomannomutase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PMM1
• Locus ID: 5372
• Kit Components:

  GA103627G1, PMM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103627G2, PMM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103627G3, PMM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002676
• Synonyms: Sec53
• Summary: 'Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008]'