Human Phosphoribosyl pyrophosphate amidotransferase (PPAT) activation kit by CRISPRa

CAT#: GA103691

PPAT CRISPRa kit - CRISPR gene activation of human phosphoribosyl pyrophosphate amidotransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPAT
• Locus ID: 5471
• Kit Components:

  GA103691G1, Phosphoribosyl pyrophosphate amidotransferase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103691G2, Phosphoribosyl pyrophosphate amidotransferase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103691G3, Phosphoribosyl pyrophosphate amidotransferase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002703, NR_156493
• Synonyms: ATASE; GPAT; PRAT
• Summary: 'The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011]'