Human MAPK6 activation kit by CRISPRa

CAT#: GA103787

MAPK6 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAPK6
• Locus ID: 5597
• Kit Components:

  GA103787G1, MAPK6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103787G2, MAPK6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103787G3, MAPK6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002748
• Synonyms: ERK3; HsT17250; p97MAPK; PRKM6
• Summary: 'The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008]'