Human PROX1 activation kit by CRISPRa

CAT#: GA103814

PROX1 CRISPRa kit - CRISPR gene activation of human prospero homeobox 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PROX1
• Locus ID: 5629
• Kit Components:

  GA103814G1, PROX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103814G2, PROX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103814G3, PROX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270616, NM_002763
• Summary: 'The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]'