Human Pregnancy Specific Glycoprotein 1 (PSG1) activation kit by CRISPRa

CAT#: GA103841

PSG1 CRISPRa kit - CRISPR gene activation of human pregnancy specific beta-1-glycoprotein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PSG1
• Locus ID: 5669
• Kit Components:

  GA103841G1, Pregnancy Specific Glycoprotein 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103841G2, Pregnancy Specific Glycoprotein 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103841G3, Pregnancy Specific Glycoprotein 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001184825, NM_001184826, NM_001297773, NM_001330524, NM_006905
• Synonyms: B1G1; CD66f; DHFRP2; FL-NCA-1/2; PBG1; PS-beta-C/D; PS-beta-G-1; PSBG-1; PSBG1; PSG95; PSGGA
• Summary: 'The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009]'