Human S6K1 (RPS6KB1) activation kit by CRISPRa

CAT#: GA104200

RPS6KB1 CRISPRa kit - CRISPR gene activation of human ribosomal protein S6 kinase B1

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

Product Images

Frequently bought together (2)
RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI6B2 (formerly 6B2)
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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol RPS6KB1
Locus ID 6198
Kit Components

GA104200G1, S6K1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104200G2, S6K1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104200G3, S6K1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001272042, NM_001272043, NM_001272044, NM_001272060, NM_003161, NR_161462, NM_001369670, NM_001369673, NM_001369675, NM_001369677, NM_001369678, NR_161455, NR_161456, NR_161460, NM_001369669, NM_001369671, NM_001369672, NM_001369674, NM_001369676, NM_001369679, NR_161457, NR_161458, NR_161459, NR_161461
Synonyms p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A
Summary 'This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.