Human Retinoid X Receptor beta (RXRB) activation kit by CRISPRa

CAT#: GA104240

RXRB CRISPRa kit - CRISPR gene activation of human retinoid X receptor beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RXRB
• Locus ID: 6257
• Kit Components:

  GA104240G1, Retinoid X Receptor beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104240G2, Retinoid X Receptor beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104240G3, Retinoid X Receptor beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270401, NM_001291989, NM_021976
• Synonyms: DAUDI6; H-2RIIBP; NR2B2; RCoR-1
• Summary: 'This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]'