Human Psoriasin (S100A7) activation kit by CRISPRa

CAT#: GA104256

S100A7 CRISPRa kit - CRISPR gene activation of human S100 calcium binding protein A7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: S100A7
• Locus ID: 6278
• Kit Components:

  GA104256G1, Psoriasin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104256G2, Psoriasin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104256G3, Psoriasin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002963
• Synonyms: PSOR1; S100A7c
• Summary: 'The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]'