Human SERPINB4 activation kit by CRISPRa

CAT#: GA104286

SERPINB4 CRISPRa kit - CRISPR gene activation of human serpin family B member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SERPINB4
• Locus ID: 6318
• Kit Components:

  GA104286G1, SERPINB4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104286G2, SERPINB4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104286G3, SERPINB4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002974, NM_175041
• Synonyms: LEUPIN; PI11; SCCA-2; SCCA1; SCCA2
• Summary: 'The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. [provided by RefSeq, Jan 2017]'