Human Macrophage Inflammatory Protein 3 alpha (CCL20) activation kit by CRISPRa

CAT#: GA104327

CCL20 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 20

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCL20
• Locus ID: 6364
• Kit Components:

  GA104327G1, Macrophage Inflammatory Protein 3 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104327G2, Macrophage Inflammatory Protein 3 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104327G3, Macrophage Inflammatory Protein 3 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130046, NM_004591
• Synonyms: CKb4; Exodus; LARC; MIP-3-alpha; MIP-3a; MIP3A; SCYA20; ST38
• Summary: 'This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]'