Human TECK (CCL25) activation kit by CRISPRa

CAT#: GA104332

CCL25 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 25

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCL25
• Locus ID: 6370
• Kit Components:

  GA104332G1, TECK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104332G2, TECK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104332G3, TECK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001201359, NM_005624, NM_148888
• Synonyms: Ckb15; SCYA25; TECK
• Summary: 'This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]'