Human SFRP2 activation kit by CRISPRa

CAT#: GA104368

SFRP2 CRISPRa kit - CRISPR gene activation of human secreted frizzled related protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SFRP2
• Locus ID: 6423
• Kit Components:

  GA104368G1, SFRP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104368G2, SFRP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104368G3, SFRP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003013
• Synonyms: FRP-2; SARP1; SDF-5
• Summary: 'This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008]'