Human EAAT1 (SLC1A3) activation kit by CRISPRa

CAT#: GA104432

SLC1A3 CRISPRa kit - CRISPR gene activation of human solute carrier family 1 member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC1A3
• Locus ID: 6507
• Kit Components:

  GA104432G1, EAAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104432G2, EAAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104432G3, EAAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166695, NM_001166696, NM_001289939, NM_001289940, NM_004172
• Synonyms: EA6; EAAT1; GLAST; GLAST1
• Summary: 'This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2014]'