Human Dopamine Transporter (SLC6A3) activation kit by CRISPRa

CAT#: GA104455

SLC6A3 CRISPRa kit - CRISPR gene activation of human solute carrier family 6 member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC6A3
• Locus ID: 6531
• Kit Components:

  GA104455G1, Dopamine Transporter gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104455G2, Dopamine Transporter gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104455G3, Dopamine Transporter gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001044
• Synonyms: DAT; DAT1; PKDYS
• Summary: 'This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009]'