Human VMAT2 (SLC18A2) activation kit by CRISPRa

CAT#: GA104490

SLC18A2 CRISPRa kit - CRISPR gene activation of human solute carrier family 18 member A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC18A2
• Locus ID: 6571
• Kit Components:

  GA104490G1, VMAT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104490G2, VMAT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104490G3, VMAT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003054
• Synonyms: SVAT; SVMT; VAT2; VMAT2
• Summary: 'This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments. [provided by RefSeq, Jun 2018]'