Human SUOX activation kit by CRISPRa

CAT#: GA104695

SUOX CRISPRa kit - CRISPR gene activation of human sulfite oxidase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SUOX
• Locus ID: 6821
• Kit Components:

  GA104695G1, SUOX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104695G2, SUOX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104695G3, SUOX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000456, NM_001032386, NM_001032387
• Synonyms: OTTHUMP00000158619; sulfite oxidase
• Summary: 'Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008]'