Human UGP2 activation kit by CRISPRa

CAT#: GA105070

UGP2 CRISPRa kit - CRISPR gene activation of human UDP-glucose pyrophosphorylase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UGP2
• Locus ID: 7360
• Kit Components:

  GA105070G1, UGP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105070G2, UGP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105070G3, UGP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001521, NM_006759
• Synonyms: pHC379; UDPG; UDPGP; UDPGP2; UGP1; UGPP1; UGPP2
• Summary: 'The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'