Human Uroplakin II (UPK2) activation kit by CRISPRa

CAT#: GA105085

UPK2 CRISPRa kit - CRISPR gene activation of human uroplakin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UPK2
• Locus ID: 7379
• Kit Components:

  GA105085G1, Uroplakin II gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105085G2, Uroplakin II gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105085G3, Uroplakin II gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006760
• Synonyms: UP2; UPII
• Summary: 'This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]'