Human valyl tRNA synthetase (VARS) activation kit by CRISPRa

CAT#: GA105103

VARS CRISPRa kit - CRISPR gene activation of human valyl-tRNA synthetase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VARS1
• Locus ID: 7407
• Kit Components:

  GA105103G1, valyl tRNA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105103G2, valyl tRNA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105103G3, valyl tRNA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006295
• Synonyms: G7A; VARS1; VARS2
• Summary: 'Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]'