Human ACOX3 activation kit by CRISPRa

CAT#: GA105478

ACOX3 CRISPRa kit - CRISPR gene activation of human acyl-CoA oxidase 3, pristanoyl

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACOX3
• Locus ID: 8310
• Kit Components:

  GA105478G1, ACOX3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105478G2, ACOX3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105478G3, ACOX3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001101667, NM_003501
• Synonyms: acyl-Coenzyme A oxidase 3, pristanoyl
• Summary: Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008]