Human FOXN1 activation kit by CRISPRa

CAT#: GA105588

FOXN1 CRISPRa kit - CRISPR gene activation of human forkhead box N1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOXN1
• Locus ID: 8456
• Kit Components:

  GA105588G1, FOXN1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105588G2, FOXN1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105588G3, FOXN1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003593, NM_001369369
• Synonyms: FKHL20; RONU; WHN
• Summary: Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, Jul 2008]