Human SHARP2 (BHLHE40) activation kit by CRISPRa

CAT#: GA105665

BHLHE40 CRISPRa kit - CRISPR gene activation of human basic helix-loop-helix family member e40

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BHLHE40
• Locus ID: 8553
• Kit Components:

  GA105665G1, BHLHE40 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105665G2, BHLHE40 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105665G3, BHLHE40 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003670
• Synonyms: BHLHB2; DEC1; HLHB2; SHARP-2; STRA13; Stra14
• Summary: This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]