Human Phosphatidic acid phosphatase type 2B (PLPP3) activation kit by CRISPRa

CAT#: GA105702

PLPP3 CRISPRa kit - CRISPR gene activation of human phospholipid phosphatase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLPP3
• Locus ID: 8613
• Kit Components:

  GA105702G1, PLPP3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105702G2, PLPP3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105702G3, PLPP3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003713, NM_177414
• Synonyms: Dri42; LPP3; PAP2B; PPAP2B; VCIP
• Summary: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells. [provided by RefSeq, Mar 2010]