Human KCNK5 activation kit by CRISPRa

CAT#: GA105728

KCNK5 CRISPRa kit - CRISPR gene activation of human potassium two pore domain channel subfamily K member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNK5
• Locus ID: 8645
• Kit Components:

  GA105728G1, KCNK5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105728G2, KCNK5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105728G3, KCNK5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003740
• Synonyms: K2p5.1; KCNK5b; TASK-2; TASK2
• Summary: This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008]