Human ADAM7 activation kit by CRISPRa

CAT#: GA105815

ADAM7 CRISPRa kit - CRISPR gene activation of human ADAM metallopeptidase domain 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADAM7
• Locus ID: 8756
• Kit Components:

  GA105815G1, ADAM7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105815G2, ADAM7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105815G3, ADAM7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003817
• Synonyms: ADAM-7; ADAM 7; EAPI; GP-83; GP83
• Summary: This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. [provided by RefSeq, Oct 2011]