Human DcR3 (TNFRSF6B) activation kit by CRISPRa

CAT#: GA105822

TNFRSF6B CRISPRa kit - CRISPR gene activation of human TNF receptor superfamily member 6b

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TNFRSF6B
• Locus ID: 8771
• Kit Components:

  GA105822G1, TNFRSF6B gRNA vector 1 in pCas-Guide-CRISPRa

  GA105822G2, TNFRSF6B gRNA vector 2 in pCas-Guide-CRISPRa

  GA105822G3, TNFRSF6B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003823, NM_015647, NM_032945
• Synonyms: DCR3; DJ583P15.1.1; M68; M68E; TR6
• Summary: This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]