Human ALKBH1 activation kit by CRISPRa

CAT#: GA105887

ALKBH1 CRISPRa kit - CRISPR gene activation of human alkB homolog 1, histone H2A dioxygenase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALKBH1
• Locus ID: 8846
• Kit Components:

  GA105887G1, ALKBH1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105887G2, ALKBH1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105887G3, ALKBH1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039506, NM_006020
• Synonyms: ABH; ABH, alkB, hABH, ALKBH; ABH1; alkB; alkB, alkylation repair homolog 1 (E. coli); ALKBH; alkylated DNA repair protein alkB homolog; alkylation repair, alkB homolog; hABH
• Summary: This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]