Human TM4SF5 activation kit by CRISPRa

CAT#: GA106003

TM4SF5 CRISPRa kit - CRISPR gene activation of human transmembrane 4 L six family member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TM4SF5
• Locus ID: 9032
• Kit Components:

  GA106003G1, TM4SF5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106003G2, TM4SF5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106003G3, TM4SF5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003963
• Synonyms: tetraspan transmembrane protein L6H; transmembrane 4 L six family member 5; transmembrane 4 superfamily member 5
• Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence and structure to transmembrane 4 superfamily member 1. It may play a role in cell proliferation, and overexpression of this protein may be associated with the uncontrolled growth of tumour cells. [provided by RefSeq, Jul 2008]