Human Claudin 9 (CLDN9) activation kit by CRISPRa

CAT#: GA106041

CLDN9 CRISPRa kit - CRISPR gene activation of human claudin 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLDN9
• Locus ID: 9080
• Kit Components:

  GA106041G1, CLDN9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106041G2, CLDN9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106041G3, CLDN9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020982
• Synonyms: claudin 9
• Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness. [provided by RefSeq, Jun 2010]