Human Melatonin Related Receptor (GPR50) activation kit by CRISPRa

CAT#: GA106168

GPR50 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor 50

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPR50
• Locus ID: 9248
• Kit Components:

  GA106168G1, GPR50 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106168G2, GPR50 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106168G3, GPR50 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004224
• Synonyms: H9; Mel1c
• Summary: This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]