Human UBE4A activation kit by CRISPRa

CAT#: GA106237

UBE4A CRISPRa kit - CRISPR gene activation of human ubiquitination factor E4A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBE4A
• Locus ID: 9354
• Kit Components:

  GA106237G1, UBE4A gRNA vector 1 in pCas-Guide-CRISPRa

  GA106237G2, UBE4A gRNA vector 2 in pCas-Guide-CRISPRa

  GA106237G3, UBE4A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204077, NM_004788
• Synonyms: E4; UBOX2; UFD2
• Summary: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]