Human NAPSIN A (NAPSA) activation kit by CRISPRa

CAT#: GA106332

NAPSA CRISPRa kit - CRISPR gene activation of human napsin A aspartic peptidase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NAPSA
• Locus ID: 9476
• Kit Components:

  GA106332G1, NAPSA gRNA vector 1 in pCas-Guide-CRISPRa

  GA106332G2, NAPSA gRNA vector 2 in pCas-Guide-CRISPRa

  GA106332G3, NAPSA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004851
• Synonyms: KAP; Kdap; NAP1; NAPA; SNAPA
• Summary: This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]