Human XAGE2 activation kit by CRISPRa

CAT#: GA106352

XAGE2 CRISPRa kit - CRISPR gene activation of human X antigen family member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: XAGE2
• Locus ID: 9502
• Kit Components:

  GA106352G1, XAGE2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106352G2, XAGE2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106352G3, XAGE2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_130777
• Synonyms: CT12.2; GAGED3; XAGE-2; XAGE2B
• Summary: This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. [provided by RefSeq, Jul 2008]