Human NRG2 activation kit by CRISPRa
CAT#: GA106386
NRG2 CRISPRa kit - CRISPR gene activation of human neuregulin 2
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | NRG2 |
Locus ID | 9542 |
Kit Components | GA106386G1, NRG2 gRNA vector 1 in pCas-Guide-CRISPRa GA106386G2, NRG2 gRNA vector 2 in pCas-Guide-CRISPRa GA106386G3, NRG2 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001184935, NM_004883, NM_013981, NM_013982, NM_013983, NM_013984, NM_013985 |
Synonyms | DON1; HRG2; NTAK |
Summary | This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010] |
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Other Versions
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KN413122 | NRG2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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