Human Synphilin 1 (SNCAIP) activation kit by CRISPRa

CAT#: GA106447

SNCAIP CRISPRa kit - CRISPR gene activation of human synuclein alpha interacting protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNCAIP
• Locus ID: 9627
• Kit Components:

  GA106447G1, SNCAIP gRNA vector 1 in pCas-Guide-CRISPRa

  GA106447G2, SNCAIP gRNA vector 2 in pCas-Guide-CRISPRa

  GA106447G3, SNCAIP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242935, NM_001308100, NM_001308105, NM_001308106, NM_001308107, NM_001308108, NM_001308109, NM_005460, NR_131761, NR_131762, N21998
• Synonyms: Sph1; SYPH1
• Summary: This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]