Human ISG15 activation kit by CRISPRa

CAT#: GA106454

ISG15 CRISPRa kit - CRISPR gene activation of human ISG15 ubiquitin like modifier

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ISG15
• Locus ID: 9636
• Kit Components:

  GA106454G1, ISG15 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106454G2, ISG15 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106454G3, ISG15 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005101
• Synonyms: G1P2; hUCRP; IFI15; IMD38; IP17; UCRP
• Summary: The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]