Human ABCB6 activation kit by CRISPRa

CAT#: GA106815

ABCB6 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily B member 6 (Langereis blood group)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABCB6
• Locus ID: 10058
• Kit Components:

  GA106815G1, ABCB6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106815G2, ABCB6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106815G3, ABCB6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005689, NM_001349828
• Synonyms: ABC; ABC14; DUH3; LAN; MCOPCB7; MTABC3; PRP; umat
• Summary: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the heavy metal importer subfamily and plays a role in porphyrin transport. This gene is the molecular basis of the Langereis (Lan) blood group antigen and mutations in this gene underlie familial pseudohyperkalemia and dyschromatosis universalis hereditaria. [provided by RefSeq, Mar 2017]