Human B3GNT3 activation kit by CRISPRa

CAT#: GA107043

B3GNT3 CRISPRa kit - CRISPR gene activation of human UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: B3GNT3
• Locus ID: 10331
• Kit Components:

  GA107043G1, B3GNT3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107043G2, B3GNT3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107043G3, B3GNT3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014256
• Synonyms: B3GAL-T8; B3GN-T3; B3GNT-3; beta3Gn-T3; HP10328; TMEM3
• Summary: This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. [provided by RefSeq, Jul 2008]