Human TRIM22 activation kit by CRISPRa

CAT#: GA107052

TRIM22 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 22

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRIM22
• Locus ID: 10346
• Kit Components:

  GA107052G1, TRIM22 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107052G2, TRIM22 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107052G3, TRIM22 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199573, NM_006074
• Synonyms: GPSTAF50; RNF94; STAF50
• Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]