Human hnRNP Q (SYNCRIP) activation kit by CRISPRa

CAT#: GA107167

SYNCRIP CRISPRa kit - CRISPR gene activation of human synaptotagmin binding cytoplasmic RNA interacting protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYNCRIP
• Locus ID: 10492
• Kit Components:

  GA107167G1, SYNCRIP gRNA vector 1 in pCas-Guide-CRISPRa

  GA107167G2, SYNCRIP gRNA vector 2 in pCas-Guide-CRISPRa

  GA107167G3, SYNCRIP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001159673, NM_001159674, NM_001159675, NM_001159676, NM_001159677, NM_001253771, NM_006372
• Synonyms: GRY-RBP; GRYRBP; hnRNP-Q; HNRNPQ; HNRPQ1; NSAP1; PP68
• Summary: This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011]