Human ARPC1A activation kit by CRISPRa

CAT#: GA107212

ARPC1A CRISPRa kit - CRISPR gene activation of human actin related protein 2/3 complex subunit 1A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARPC1A
• Locus ID: 10552
• Kit Components:

  GA107212G1, ARPC1A gRNA vector 1 in pCas-Guide-CRISPRa

  GA107212G2, ARPC1A gRNA vector 2 in pCas-Guide-CRISPRa

  GA107212G3, ARPC1A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190996, NM_006409
• Synonyms: Arc40; HEL-68; HEL-S-307; SOP2Hs; SOP2L
• Summary: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]