Human GMEB1 activation kit by CRISPRa

CAT#: GA107331

GMEB1 CRISPRa kit - CRISPR gene activation of human glucocorticoid modulatory element binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GMEB1
• Locus ID: 10691
• Kit Components:

  GA107331G1, GMEB1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107331G2, GMEB1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107331G3, GMEB1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001319674, NM_006582, NM_024482
• Synonyms: P96PIF; PIF96
• Summary: This gene encodes a member of KDWK gene family which associates with GMEB2 protein. The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. Studies in rat for a similar gene suggest that this gene's role is to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Three alternative spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Feb 2016]