Human NUP50 activation kit by CRISPRa

CAT#: GA107373

NUP50 CRISPRa kit - CRISPR gene activation of human nucleoporin 50

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NUP50
• Locus ID: 10762
• Kit Components:

  GA107373G1, NUP50 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107373G2, NUP50 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107373G3, NUP50 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007172, NM_153645, NM_153684
• Synonyms: NPAP60; NPAP60L
• Summary: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]