Human IQGAP2 activation kit by CRISPRa

CAT#: GA107393

IQGAP2 CRISPRa kit - CRISPR gene activation of human IQ motif containing GTPase activating protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IQGAP2
• Locus ID: 10788
• Kit Components:

  GA107393G1, IQGAP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107393G2, IQGAP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107393G3, IQGAP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001285460, NM_001285461, NM_001285462, NM_006633
• Summary: This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]