Human CFHR3 activation kit by CRISPRa

CAT#: GA107451

CFHR3 CRISPRa kit - CRISPR gene activation of human complement factor H related 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CFHR3
• Locus ID: 10878
• Kit Components:

  GA107451G1, CFHR3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107451G2, CFHR3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107451G3, CFHR3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166624, NM_021023
• Synonyms: CFHL3; DOWN16; FHR-3; FHR3; HLF4
• Summary: The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]