Human OGFR activation kit by CRISPRa

CAT#: GA107594

OGFR CRISPRa kit - CRISPR gene activation of human opioid growth factor receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OGFR
• Locus ID: 11054
• Kit Components:

  GA107594G1, OGFR gRNA vector 1 in pCas-Guide-CRISPRa

  GA107594G2, OGFR gRNA vector 2 in pCas-Guide-CRISPRa

  GA107594G3, OGFR gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007346
• Synonyms: 7-60 protein; opioid growth factor receptor; OTTHUMP00000031503; zeta-type opioid receptor
• Summary: The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008]