Human CIT activation kit by CRISPRa

CAT#: GA107642

CIT CRISPRa kit - CRISPR gene activation of human citron rho-interacting serine/threonine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CIT
• Locus ID: 11113
• Kit Components:

  GA107642G1, CIT gRNA vector 1 in pCas-Guide-CRISPRa

  GA107642G2, CIT gRNA vector 2 in pCas-Guide-CRISPRa

  GA107642G3, CIT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206999, NM_007174
• Synonyms: CITK; CRIK; MCPH17; STK21
• Summary: This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]